Read e-book online ADAMTS13: Biology and Disease PDF

By George M. Rodgers

ISBN-10: 3319087169

ISBN-13: 9783319087160

ISBN-10: 3319347306

ISBN-13: 9783319347301

This accomplished quantity discusses the protease ADAMTS13, summarizing the present prestige of uncomplicated and medical study. The 9 authoritative chapters start with a old viewpoint by way of exploration of the biochemistry and structure-function relationships of ADAMTS13 in addition to its general functionality in hemostasis (cleavage of von Willebrand factor). rising examine topics for ADAMTS13 are lined, together with its strength position in angiogenesis and different points of telephone biology. extra issues contain laboratory assays for ADAMTS13, inherited ADAMTS13 deficiency, and bought ADAMTS13 deficiency. A bankruptcy on similar thrombotic microangiopathic (TMA) problems examines the variations among TMAs linked to ADAMTS13 deficiency and people no longer linked to ADAMTS13 deficiency. a last bankruptcy reports the initial details on rising features of ADAMTS13, comparable to the prestige of recombinant ADAMTS13 items and their strength utility.


Comprehensive in its exploration of the ADAMTS13 protease in disease, ADAMTS13: Biology and affliction is an important source for scientific hematologists, transfusion drugs physicians, and researchers attracted to hemostasis, vascular biology, biochemistry, and metalloproteases.

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ADAMTS13: Biology and Disease by George M. Rodgers

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